12th Mar 2010

How are okazaki fragments of a DNA strand made ?

  • can someone please explain to me how okazaki fragments are formed ?


  • u got the answer...... no, i think this video on youtube will help u to understand the entire process clearly.......http://www.youtube.com/watch?v=teV62zrm2...


  • Okazaki fragments are the small DNA pieces formed between RNA primers during discontinuous replication on the lagging strand.

    Basically, because DNA Polymerase can only work in one direction (it needs an open 3' end to add nucleotides to), it can't just add nucleotides to the side that has an open 5' end. Instead, Primase adds multiple RNA primers and then DNA Polymerase works backwards, between the primers. These DNA nucleotides that are put in place between the primers are the Okazaki fragments.







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