12th Mar 2010
How are okazaki fragments of a DNA strand made ?
Basically, because DNA Polymerase can only work in one direction (it needs an open 3' end to add nucleotides to), it can't just add nucleotides to the side that has an open 5' end. Instead, Primase adds multiple RNA primers and then DNA Polymerase works backwards, between the primers. These DNA nucleotides that are put in place between the primers are the Okazaki fragments.
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Posted by smith under enart.88083.com |